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发表于 2012-8-14 00:55
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其实比饶毅更牛的回复是 Upenn 的 LAI JIANG
# ^% S. A- B; s u如果是中国长大的,英语能到这种程度真是很不简单。
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http://www.sas.upenn.edu/rappegroup/htdocs/People/LJ.html
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FROM LAI JIANG, Department of Chemistry, University of Pennsylvania! O3 X( B6 }. y% ^) Q, w- A
2 n! V# }* S; A- S# `It is a shame to see Nature — which nearly all scientists, including myself
* B' a- d3 T5 A4 U) [* H, regard as one of the most prestigious and influential physical-science% |0 F1 p9 j2 W$ o
magazines — publish a thinly veiled biased article like this. Granted, this% r5 u0 {4 s( S% v! q! |7 j
is not a peer-reviewed scientific article and did not go through the8 o, o) _& e) D7 s Q
scrutiny of picking referees. But to serve as a channel for the general
) `+ a$ g) d- [' @* y- e) C, {, rpopulace to be in touch with and appreciate science, the authors and editors
. u% E0 L- a% G7 Oshould at least present the readers with facts within the proper context,; l8 h, A! N* Z- C- n3 c
which they blatantly failed to do.% _9 g( x8 ~" {8 Q$ z+ r2 W/ r
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First, to identify Ye’s performance increase, Ewen Callaway compared her
# x) D. C5 q; E) i+ H% f& c# SOlympic 400-metre IM time with her performance at the World Championships in
6 H9 s' s; M8 o, T2011 (4:28.43 and 4:35.15, respectively) and concluded that she had an “
; k% C5 ~2 O3 c' w) E( j: Yanomalous” improvement of around 7 seconds (6.72 s). In fact, her previous0 | o. [& t) q+ _/ x
personal best was 4:33.79 at the Asian Games in 2010. This leads to an
4 c6 y: Z& t( B S0 jimprovement of 5.38 seconds. In a sporting event in which 0.1 s can be the- W7 ?8 p' |7 O/ v5 P
difference between the gold and silver medal, I see no reason for 5.38 s to1 |* ~" I& B5 u3 t9 h' P8 U( F
be treated as 7 s.5 d+ K5 n$ a0 C* ^3 |; C# K
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Second, as previously pointed out, Ye is only 16 years old and her body is
/ L7 X; j4 N: c7 P( Astill developing. Bettering oneself by 5 seconds over two years may seem+ E4 H# M o. ~. {8 {
impossible for an adult swimmer, but it certainly happens among youngsters.
% }9 E) U* j& _9 sAn interview with Australian gold medallist Ian Thorpe revealed that his 4002 F7 F& z% U; L* M0 E) I
-metre freestyle time improved by 5 seconds between the ages of 15 and 16.- f; G( X2 D5 y8 ~( S
For regular people, including Callaway, it may be hard to imagine what an' e: Q3 C! B# R9 q
elite swimmer can achieve as he or she matures and undergoes scientific and
) v5 Q1 A% g% C( M' x: E% Upersistent training. But jumping to the conclusion that it is “anomalous”4 l, }; c% e3 o
based on ‘Oh that’s so tough I cannot imagine it is real’ is hardly sound.7 U! i% d2 U& [! y3 i
! i6 u1 \& M# i# M/ G6 i2 PThird, to compare Ryan Lochte’s last 50 metres to Ye’s is a textbook
9 N7 s" Y( ~$ `( f" H1 l# j- l" {example of ‘cherry-picking’ your data. Yes, Lochte was slower than Ye in- m1 a# O, Q9 D5 B+ x
the last 50 metres, but Lochte had a huge lead in the first 300 metres, so$ ?5 J5 w' ^3 W% s" V0 h: [; s) }
he chose not to push himself too hard and to conserve his energy for later
: M' G: `7 M; @1 i! A# {events (whether this conforms to the Olympic spirit and the ‘use one’s
8 Z2 p6 N% g0 d, t. ^best efforts to win a match’ requirement that the Badminton World4 @8 U& o }+ [ _* s1 s9 _
Federation recently invoked to disqualify four badminton pairs is another
. K4 |9 M8 s, D8 ]topic worth discussing, though probably not in Nature). Ye, on the other9 M/ A, t" M0 x; Z
hand, was trailing behind after the first 300 metres and relied on freestyle# i8 g1 g2 S* _/ Z; t
, in which she has an edge, to win the race. Failing to mention this! S- M5 ?" \1 B6 _
strategic difference, as well as the fact that Lochte is 23.25 seconds
2 T% P5 D) P( L [3 Afaster (4:05.18) than Ye overall, creates the illusion that a woman swam! p N5 ?9 o3 H/ q7 V3 Q* T7 ?' ]. B
faster than the best man in the same sport, which sounds impossible. Putting
8 o, q, m. y3 F6 [/ Baside the gender argument, I believe this is still a leading question that" c p; r: R( ~) j% o$ \- A+ }. V
implies to the reader that there is something fishy going on.2 U" `* W# r1 r' H3 ]; C
3 c# h5 [ f: U& j- j) L7 sFourth is another example of cherry-picking. In the same event, there are' t4 W# c! n P _7 P. E
four male swimmers who swam faster than both Lochter (29.10 s) and Ye (28.93
* y) ~8 H4 x$ G# @8 m/ q6 ds) in the final 50 metres: Kosuke Hagino (28.52 s), Michael Phelps (28.44 s* q3 t9 @, O, {( A; B* |
), Yuya Horihata (27.87 s) and Thomas Fraser-Holmes (28.35 s). As it turns
0 y A J8 U7 `/ Xout, if we are just talking about the last 50 metres in a 400-metre IM,
, v. F4 b( q( ULochter is not the example I would have used if I were the author. What kind; \" v1 [$ M' J' k$ A! A( N
of scientific rigorousness is Callaway trying to demonstrate here? Is it9 R" i+ `. \2 v
logical that if Lochter is the champion, we should assume that he leads in
+ ^. W/ Y, r+ h0 ~8 s9 nevery split? That would be a terrible way to teach the public how science
+ |9 \: [3 b. w" Aworks.
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Fifth is the issue I oppose the most. Callaway quotes Ross Tucker and( |! ]$ B, ~3 c; E% Q' x# z+ g
implies that a drug test cannot rule out the possibility of doping. Is this
$ a i" D. U+ f ckind of agnosticism what Nature really wants to teach its readers? By that
2 K, s# [! ?, K5 hstandard, I estimate that at least half of the peer-reviewed scientific) i8 R& [/ y, P! q4 g7 u$ H
papers in Nature should be retracted. How can one convince the editors and( u. U$ P1 h# u2 R! R" H
reviewers that their proposed theory works for every possible case? One
$ E. i# [1 j# _3 T9 Ycannot. One chooses to apply the theory to typical examples and to; W) B ~9 R- X4 v
demonstrate that in (hopefully) all scenarios considered, the theory works9 v. ~/ ?8 Q$ m* F, d6 R) s1 b
to a degree, and that that should warrant publication until a counterexample8 s0 Q0 a5 A( g2 _- c$ \# R2 t. \: O
is found. I could imagine that Callaway has a sceptical mind, which is1 M- `7 h! v- X# F) v6 R; L3 r u
crucial to scientific thinking, but that would be put to better use if he. Q7 ]% D# H9 Z- w: L) T% j9 t
wrote a peer-reviewed paper that discussed the odds of Ye doping on a highly
$ v8 E- J7 r, K/ Q1 a7 W0 Sadvanced, non-detectable drug that the Chinese have come up with in the
1 {* P- T1 J2 m0 Q! Npast 4 years (they obviously did not have it in Beijing, otherwise why not4 |/ H2 ]2 c9 F
use it and woo the audience at home?), based on data and rational derivation6 ?9 X# A: i/ I
. This article, however, can be interpreted as saying that all athletes are' y6 [# \1 g s9 e V4 H
doping and the authorities are just not good enough to catch them. That may
3 o+ o' U' `7 d8 z* r& K" M% Sbe true, logically, but definitely will not make the case if there is ever a/ n6 K8 T, u8 F" E2 y! M4 a
hearing by the governing body for water sports, FINA, to determine if Ye7 y8 w8 t, I4 O9 B$ M2 o
has doped. To ask whether it is possible to obtain a false negative in a& |$ `) E: q. R8 @ x0 O- b+ W
drug test looks like a rigged question to me. Of course it is possible:
7 o6 |( `4 b4 `- uother than the athlete taking a drug that the test is not designed to detect
% p9 E) ~3 a9 F: w2 ?, anyone who has taken quantum 101 will tell you that everything is0 ^- I$ _* e2 j6 I: S, B
probabilistic in nature, and so there is a probability that the drug in an
% [# J' v9 s; p! n3 Eathlete’s system could tunnel out right at the moment of the test. A slight
! P! C1 |& `" h1 x7 ?chance it may be, but should we disregard all test results because of it?2 W- ^$ C3 R6 L4 k2 T5 Z
Let’s be practical and reasonable, and accept that the World Anti-Doping9 N! V b$ P2 k5 B
agency (WADA) is competent at its job. Ye’s urine sample will be stored for
5 q R$ |7 a2 reight years after the contest for future testing as technology advances.
( y6 {* a) [6 r, t; C+ F& n" j. LInnocent until proven guilty, shouldn’t it be?
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Sixth, and the last point I would like to make, is that the out-of-
- Y1 k( N* t" [5 Xcompetition drug test is already in effect, which Callaway failed to mention( y8 k6 N6 d6 {' Y; m
. As noted in the president of WADA’s press release, drug testing for
4 B8 S) C' v+ B* |9 u5 z; XOlympians began at least six months before the opening of the London
" W% o) m" H5 w, ~6 fOlympics. Furthermore, 107 athletes have been banned from this Olympics for
+ O; l L* B+ zdoping. That may be the reason that “everyone will pass at the Olympic
% }* i/ x4 p3 U2 @2 |games. Hardly anyone fails in competition testing” — those who did dope
' m) F& n7 ]4 t8 [) R) q) zhave already been caught and sanctioned. Callaway is free to suggest that a7 Y4 t0 M# `. t5 N l
player could have doped beforehand and fooled the test at the game, but this% I/ }) P8 C0 E, l _8 y* E0 v; Q
possibility is certainly ruled out for Ye.
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Over all, even though Callaway did not falsify any data, he did (( u4 u3 y% V% f! H
intentionally or not) cherry-pick data that, in my view, are far too" s& _: `/ z! y) d4 z
suggestive to be fair and unbiased. If you want to cover a story of a
6 M4 T8 g9 a* K; Y/ _* asuspected doping from a scientific point of view, be impartial and provide
9 H8 F7 ^* B/ G5 S1 pall the facts for the reader to judge. You are entitled to your: C, G, ^; R1 I# {/ K1 W
interpretation of the facts, and the expression thereof in your piece,! N/ k* o; }; y. w- O9 x+ ~$ r$ i
explicitly or otherwise, but showing only evidence that favours your
% t2 V5 X: A; [3 x1 m# Margument is hardly good science or journalism. Such an article in a journal
! l& V" R9 d1 @0 S5 rsuch as Nature is not an appropriate example of how scientific research or/ c- I: }& D0 s0 ]( e; e0 l# v
reporting should be done. |
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