Postdoctoral position in single molecule biophysics

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Postdoctoral fellow
University of Alberta and National Institute for Nanotechnology
, ]7 g: c# @* B" xEdmonton, Alberta, Canada
$ {4 g2 z, T$ M8 N# a/ xJob ID: 6926659
3 H* B% |/ x. i& i4 D$ a; \2 WJob Duration: 1-2 Years
8 j. j1 Y; E; k& K- ?% Q, F+ xPosition Title: Postdoctoral fellow
Required Travel: None
% f+ U) n$ S4 I2 mMin Education: Ph.D.
Posted: June 23, 2010
7 O9 n7 `) P; M* [" t; a3 D1 E, V( JJob Function: Postdoc
Min Experience: None
Job Type: Full-Time
: i% I0 W+ i) m. y  ^3 fSalary: Yearly Salary)
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Postdoctoral position in single molecule biophysics: protein folding and aggregation studies
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A postdoctoral position in single-molecule biophysics is available immediately at the Department of Physics, University of Alberta and the National Institute for Nanotechnology, in the research group of Michael Woodside. A talented experimentalist is sought to conduct research into protein folding, misfolding, and aggregation, primarily using single-molecule fluorescence techniques. The successful candidates will work with a team of technicians and other researchers (at the University, the Institute, and in industry) to characterize the folding and aggregation behaviour of various disease-related proteins and to explore the effects of potential drugs on the folding/misfolding. These studies will be done using fluorescence spectroscopies (e.g. FCS and FRET), optical tweezers, and standard biochemical approaches. Responsibilities will include designing experiments; operating, maintaining, and improving instrumentation (as needed); analyzing data and writing papers; and working with other team members to translate experimental results into methods for studying drug candidates.

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; I) ?2 ~9 L1 J$ P/ m& ~The National Institute for Nanotechnology is Canada’s flagship research institute in nanotechnology. It is located on the campus of the University of Alberta, in the provincial capital, Edmonton. A city of 1 million people, Edmonton has a lively cultural scene, and it also offers numerous opportunities for outdoors enthusiasts, especially in the unrivalled beauty of nearby Jasper and Banff national parks.
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To apply, send a cover letter, curriculum vitae, and contact information (names, positions, phone numbers, mail and email addresses) for three references to Michael Woodside at michael.woodside@nrc-cnrc.gc.ca.
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Job Requirements

Motivated candidates with an interest in interdisciplinary research should have received a Ph.D. in physics, chemistry, biochemistry, biology or a closely related field within the last 2-3 years. Candidates should demonstrate a strong experimental record, with experience in single-molecule biophysics, fluorescence spectroscopy, force spectroscopy, laser optics, or protein folding, and should have a desire to learn and apply new techniques. Prior experience with single-molecule fluorescence methods would be particularly valued. Experience in molecular biology is helpful but not required, as technical support will be available in a fully-equipped biochemistry lab. The position is expected to last for at least 2 years.
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4 h* E0 ?3 L+ E- M: U8 ~# |; [Contact Person: Michael Woodside
: l9 c( t8 C7 r9 I. b, XEmail Address: michael.woodside@nrc-cnrc.gc.ca
Phone: 780-641-1695

2 [$ p( K+ K7 z6 U) _Employment Opportunity / City of Edmonton Community Services
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